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Denestra SAMe is a dietary supplement that contains S-Adenosylmethionine (SAMe), a naturally occurring compound found in the body. SAMe plays a vital role in various biochemical processes, including the production of neurotransmitters and the maintenance of cell membranes.


Key Benefits:

  1. Liver Health: SAMe is known for its positive effects on liver health. It supports the production of glutathione, a powerful antioxidant that helps protect liver cells from damage caused by toxins, medications, and oxidative stress.
  2. Mood and Emotional Well-being: SAMe is involved in the synthesis of neurotransmitters such as serotonin, dopamine, and norepinephrine, which are crucial for regulating mood and emotions. Supplementing with SAMe may help improve mood, reduce anxiety, and alleviate symptoms of depression.
  3. Joint Health: SAMe has anti-inflammatory properties that can help reduce joint pain and inflammation. It is often used as a complementary therapy for conditions like osteoarthritis, where it can support joint mobility and promote overall joint health.
  4. Cognitive Function: SAMe is believed to have neuroprotective properties and may help support cognitive function and memory. It is being investigated for its potential benefits in conditions such as Alzheimer's disease and age-related cognitive decline.
  5. Energy and Vitality: SAMe is involved in the production of adenosine triphosphate (ATP), which is the body's primary energy source. By supporting ATP production, SAMe may help improve energy levels, promote vitality, and reduce fatigue.


It's important to note that individual results may vary, and it's always recommended to consult with a healthcare professional before starting any new dietary supplement.

    Denestra SAMe (60 Tablets)

    $24.99 Regular Price
    $22.49Sale Price
    Price Options
    One-time purchase
    1 Month
    $19.12every month until canceled
    2 Month
    $20.24every 2 months until canceled
    3 Month
    $20.24every 3 months until canceled
    6 Month
    $20.24every 6 months until canceled
    • Denestra should be administered on an empty stomach, one hour before or two hours after a meal (overnight fast is preferred). Do not cut or crush tablets. May be disguised in treats for easier administration at any time at the recommendation of your Veterinarian. 

      Directions for Use 100mg:
      Size of Animal Daily
      Under 15 lb 1 Tablet
      15 - 35 lb 2 Tablets
      Directions for Use 200mg:
      Size of Dog Daily
      15 - 35 lb 1 Tablet
      36 - 65 lb 2 Tablets
      66 - 100 lb 3 Tablets
      Over 100 lb 4 Tablets
      Directions for Use 400mg:
      Size of Dog Daily
      35 - 65 lb 1 Tablet
      66 - 100 lb 2 Tablets
      Over 100 lb 3 Tablets


    • Denestra 100mg:
      Active Ingredients pet (Tablet):
      S-Adenosylmethionine (SAMe) tosylate disulfate .... 200 mg
      Denestra 200mg:
      Active Ingredients pet (Tablet):
      S-Adenosylmethionine (SAMe) tosylate disulfate .... 200 mg
      Denestra 400mg:
      Active Ingredients pet (Tablet):
      S-Adenosylmethionine (SAMe) tosylate disulfate .... 200 mg



      Inactive Ingredients: Cellulose, Citric Acid, Mannitol, Modified Cellulose Gum, Silica, Sodium Starch Glycolate, Stearic Acid. (Coating Ingredients: Hydroxypropyl Methylcellulose Phthalate or Hydroxypropyl Methylcellulose and Methacrylic Acid Copolymer, Titanium Dioxide, Triacetin, and Yellow Ochre).

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